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Currently, for non-tobacco nicotine products (i.e., those using synthetic nicotine) to be marketed legally, they must also get pre-market FDA authorization

youth has been attributed in part to the heavy marketing of these products with youth-resonating themes, as well as the widespread availability of youth-appealing flavors." In January, the National Academies of Sciences, Engineering and Medicine issued a report saying that e-cigarettes may be a less dangerous way to use tobacco, and may help established smokers reduce their immediate risk of death and disease, but they can hook teens and young adults and raise their risk of becoming smokers.

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The Interdependence of Cigarette and Liquor Demand