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In the same vein, it should be noted that cotinine, a metabolite of nicotine, but without its addictive properties, has been shown to have similar antiinflammatory effects as nicotine and hence cotinine or selective nAChR agonists or even varenicline, a partial alpha4beta2 agonist used for smoking cessation may be potential substitutes for nicotine [83, 84]

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Plants grow to about 6 feet in height and produce leaves that average 12 inches wide and 24 inches long