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Personal use as an alternative to traditional tobacco smoking Recreational use for nicotine consumption Use in electronic nicotine delivery systems (ENDS) for vapor production Vaping and E-cigarette Industry Consumer Goods Retail (Specialty Vape Shops, Convenience Stores, Online Retailers) Pharmaceutical (in some regulatory contexts, though primarily consumer) This section describes the development over the past 3 years, focusing on global imports of the chosen product in US$ terms, aggregating data from all countries

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Quantitative Real-Time PCR (qRT-PCR) was performed with a Biozym Blue SGreen master mix (331416XL, Biozym Scientific, Hessisch Oldendorf, Germany) on a BioRad CFX Opus 96 System

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