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Its high oral bioavailability provides a definite economic advantage compared with other MRSA therapeutic options, allowing earlier hospital discharge and reducing out-patient therapy cost

confirming my original speculation

Soon, the Zig-Zag Man was popping up on numerous counterculture posters and flyers most famously in June 1966 when underground artists Stanley Mouse and Alton Kelly used the image on a handbill for a pair of concerts by Big Brother and the Holding Company at San Franciscos Avalon Ballroom

Nicotinamide may also rescue NAD + depletion secondary to an ultra-rare inborn error of glutamine metabolism (78)