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The FDA's clearance of the products is a "major milestone in our efforts to drive meaningful change in the tobacco industry," Michael Zercher, president and COO of 22nd Century, said in a statement

WHO Technical Manual on Tobacco Tax Policy and Administration

We had 81.5%, 92.9%, and 84.6% reviewer concordance during title/abstract screening and 88.9%, 94.4%, and 97.7% reviewer concordance for full-text screening of studies on head and neck cancers, stroke, and ischemic heart disease, respectively