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However, it is a common effect reported by many smokers

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In fact, many landlords and property managers choose to install them to detect smoking in non-smoking units and common areas

Interestingly, long-term nose-only exposure for 1 month caused a significant increase of ROS in the heart accompanied with decreased heart GSH concentrations in exposed mice, indicating depletion of the antioxidant, which increases heart tissue's vulnerability to oxygen free radical damage [199]