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The ubiquitinproteasome system (UPS) serves as a key therapeutic target in oncology and supports the development of several novel anticancer agents

The World Bank estimates that one-third of the worlds adult population smokes an astonishing 80 percent of whom live in low- and middle-income countries. And that number just keeps growing in places like Indonesia, where a smoking household will spend about 11 percent of its income on cigarettes and the rate of smokers between the tender age of 5 and 9 has dramatically risen since 2001