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Interestingly, we found that NIC was able to suppress sperm motility already at a concentration about 10 times lower than those present in the semen of men passively exposed to cigarette smoke which has been reported to be about 10 ng/ml (Pacifici et al., As a whole, these data suggest that cigarette smoke and, in particular, NIC may cause male infertility by altering sperm motility and some parameters not evident by standard examination of the seminal fluid, such as sperm chromatin/DNA integrity

This condition causes the airway "gateway" to be significantly narrowed, increasing the likelihood of airway collapse during sleep, a central factor in the formation of sleep apnoea smoking

For example: smoking peaked in the '50s and has been declining ever since

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