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In total, the stores received for sale, offered for sale or sold more than 7,500 devices in violation of the law

Most of the studies (12 of 14) measured puffing topography in controlled environments, where puffing behavior may or may not represent e-cigarette use behavior in the real world. Two observational studies characterized puffing topography of experienced e-cigarette users of first-generation devices in their naturalistic environments

Statistical software used Prism v.6 (GraphPad Software, Inc., San Diego,CA) Study approval Informed consent was obtained from all surgical participants as part of an approved ongoing research protocol by the ethical committee of Jikei University School of Medicine in full accordance with the declaration of Helsinki principles

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