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This analysis of drug harms in Canada found that alcohol causes the most harm overall Alcohol was followed by tobacco, nonprescription opioids (like fentanyl), cocaine, methamphetamine, and cannabis. Tobacco ranked first in 4 of the 16 harm categories: drug-related mortality, drug-specific damage to physical health, dependence, and environmental damage, the researchers wrote

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Common Local Rules to Watch Local tobacco ordinances to watch out for include: A 1,000-foot buffer from schools A 500-foot buffer between tobacco retailers to prevent clustering Density caps like one tobacco retailer per 2,000 residents Pharmacy bans prevent tobacco sales at locations that also operate as a pharmacy Outright vape bans in cities like San Francisco, San Mateo County, and others How to Apply for Your California Tobacco License The CDTFA has fully digital licensing through its Online Services Portal