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Two variants of the Neo THP consumable rod with different nicotine contents were used with an identical heating device: The THP1.0(RT) consumable rod yielded 0.46 mg nicotine/stick and THP1.1(RT) yielded 0.68 mg nicotine/stick, as measured under a modified Health Canada Intense machine smoking regime (55 mL puff volume, 30 s puff interval, 2 s puff duration, 8 puffs, no vent blocking) 22,48

Arch Environ Contam Toxicol 50:205212 Mittler R, Vanderauwera S, Gollery M, Van Breusegem F (2004) Reactive oxygen gene network of plants

It also found that dual use of cigarettes and e-cigarettes was riskier than using either product alone

No one could predict what came next in their songs. Quite frankly, I could not decipher when one song ended and the next one started partly because I tuned them out because my ears were in physical pain from the cacophony