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Similar results were found showing that the nicotine dependence was higher among dual and triple users than exclusive users (Supplementary file Table 2)

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The analysis will be repeated with caregiver level differences between groups included as covariates

After that, smuggling declined, probably to less than 5% of sales in 2005.[viii] Incorporating these contraband figures smooths out the 1990s dip in legal sales shown in Figure 1, and it is reasonable to conclude that Italian consumption was fairly steady, at about 2kg per person per annum, throughout the 1980s and 1990s and only really started to decline after about 2000 Smoking and mortality Another way to measure smoking prevalence is via mortality figures as lung cancer rates tend to run about parallel to smoking ones with a lag of 20 years or so