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Smoking-related disease causes nearly one in five premature deaths in the United States (CDC)

Moreover, the role of regulatory environments is evident in regional comparisons across Southeast Asia, where adolescent e-cigarette use is lowest in Thailand (3.36.7%), where strict bans are in place, and highest in Indonesia (10.711.8%), where legal sales are permitted although heavily taxed [45, 46]

While this process is effective for reducing a little portion of the tar, it is not at all selective for individual compounds, particularly the gaseous and vapour phase components of cigarette smoke

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