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421 Notably, dotinurad has demonstrated safety in patients with an estimated glomerular filtration rate (eGFR) between 60 ml/min and 30 ml/min, without necessitating any dosage adjustments

In such cases, organ-sparing surgical procedures, Chemoradiotherapy, or radiotherapy alone can provide the possibility of laryngeal preservation while maintaining overall survival rates (38)

University of Miami [edit] In 1984, Johnson was hired by the University of Miami to replace former coach Howard Schnellenberger, who had won Miami's first national championship in 1983 and departed for the recently formed USFL