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48, 49 Probably, the effects on DC numbers are confined to the regions in close contact to the inhaled tobacco smoke, such as airway lumen, mucosa, and peribronchial tissue, and less detectable on whole lung tissue specimens

But as e-cigarettes have gained popularity and researchers have begun studying their long-term effects, theyve found evidence linking vaping to potential dangers to the heart, respiratory system, and brainand suggesting that, regardless of Juuls claimed mission to help adult smokers quit, e-cigarette use can lead younger people to take up smoking