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The NCBI (National Center for Biotechnology Information) database (2014 edition) and the HMP Unified Metabolic Analysis Network 2 (HUMAnN2) were used to annotate the nonredundant gene sets and the functional genes into Kyoto Encyclopedia of Genes and Genomes metabolic pathways, generating the metabolic pathway compositions ( Statistical Analysis Statistical analyses were performed using R (version 4.0.2)

Older research suggested that changes in blood flow to the brain could be responsible

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