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Understanding Odor Sensitivity and Migraines A range of smells and odors have been found to be problematic for some migraine sufferers such as: Perfume Cigarette smoke Paint thinner Cleaning products Car exhaust Gasoline Data varies, but clinical studies report that anywhere between 25 50% percent of migraine sufferers experience a heightened sensitivity to odors during their migraine headaches, and up to 50% report that strong smells or odors can trigger acute migraine attacks