Promote a product that is based on an addictive psychoactive substance (nicotine) Ditto Portray a toxic product as having a credible function as a benign form of self-medication Ditto Market an adult activity to youth, covertly when not permitted to do so overtly Ditto Use junk science to reduce the perception of harm and falsely claim product safety Ditto Promote smokeless products and vaping when interest in smoking wanes Ditto Profit most from lifelong, heavy users and, thus, target the youth market Ditto Big money interests use political clout to co-opt the regulatory system, proliferate and then protect a multi-billion-dollar industry that does no objective social good and actually harms the publics health Ditto Portray an inherently worthless, corrosive product as something that actually empowers, betters and liberates its users Ditto Demonize opponents as hysterical petty tyrants Ditto Remember Big Tobacco

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Materials and methods E-cigarette liquids E-cigarette liquids were prepared the same for in vitro exposure of cell cultures and in vivo whole-body exposure of mice
In the US alone, 19.7 million American adults (aged 12 and older) battled a substance use disorder in 2017, according to the National Survey on Drug Use and Health (NSDUH)