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10 Prior research using PROMIS has shown important associations with clinical outcomes, including lung function and 6-minute walk distance (6MWD) in individuals with COPD, 11,12 and HRQoL has been shown to vary with tobacco use in the general population

The gender gap in smoking has narrowed considerably since the 1970s, however (Giovino 2004)

A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic profiles of cigarettes and e-cigarettes with nicotine salt formulations in US adult smokers

It has really advantages when reducing leakage as well, as the pod integrity is not compromised and protected by a single silicone stopper that can be difficult to open