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Nicotine, the main addictive substance found in tobacco products and e-cigarettes, undergoes a complex metabolism process in the body, starting with quick absorption and concluding with its elimination through metabolic pathways

Despite these recommendations, research has shown that many healthcare professionals are still not comfortable bringing this advice into practice, likely due to a perceived lack of evidence on the safety of e-cigarette use in pregnancy specifically (Cooper et al., 2019)

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