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Unscheduled DNA synthesis, induced by the N -acetoxy-2-acetylamino- fluorene, was inhibited by ethylene oxide in human lymphocytes in vitro (Pero et al., 1981)

To prepare for the role of George Smiley, Oldman gained 15 pounds, watched Alec Guinness's performance in Tinker Tailor Soldier Spy , and paid a visit to Smiley's creator John le Carr to perfect the character's voice