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The oxidative damage of cardiolipin-sensitized mitochondria to calcium, induced mitochondrial permeability transition and destroyed the permeability barrier of IMM, which caused the collapse of mitochondrial potential, the decoupling of OXPHOS and apoptosis, and the release of cytochrome C to cytosol 83,84

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Engineering a novel probiotic toolkit in escherichia coli nissle 1917 for sensing and mitigating gut inflammatory diseases