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To confirm that the gut microbes were indeed major regulators of weight gain in the smoking cessation mice, the researchers collected microbiomes from smoking or smoking-cessation mice at various timepoints, and transferred these into germ-free mice that had never been exposed to cigarette smoke

I'll spare you the boring sciencey details

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How to determine the best dose for smoking cannabis When searching for the correct dose for smoking, ask yourself: What are my goals for smoking cannabis