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They wrote: "Most studies were funded or otherwise supported/influenced by manufacturers of [e-cigarettes], but several authors had also been consultants for manufacturers of medicinal smoking cessation therapy." When I asked one of the review's authors, Martin Dssing, what he made of the current evidence base on e-cigarettes, he said, "The literature is very poor." He continued: "The most worrying aspect of e-cigarettes is that we do not know the long-term health consequences of daily use

Our oral cavity is the most negatively affected region with smoking due to the mouths exposure to toxins in cigarettes while smoking

**In 2000, chewing tobacco and pinch/snuff were asked as separate questionnaire items and combined in the analysis

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