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Studies on Swedish snus users have shown that the plasma steady-state levels of nicotine and its main metabolite, cotinine, are similar in Swedish snus users and cigarette smokers

1880: The rise of cigarettes The tobacco industry exploded when a machine was first patented to mass-produce paper cigarettes

Participants will then rate the taste of only the cigarettes they were provided with (using the same questions as on the taste-test on Test Day 1) and complete questions taken from the previous study assessing real-world smoking behavior using plain packaging [2], which will include reporting their experience of using the topography monitor, experiences of smoking from the cigarette pack, experiences of smoking in general, attributes of the cigarette pack and perceptions of the on-packet health warnings (all on a five-point Likert scale), behavior changes (a series of binary questions), and views on plain packaging legislation (on a four-point Likert scale)

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