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Smoking: Progressive Lung Damage and Respiratory Decline Smoking causes cumulative structural and functional damage to the respiratory system through chronic exposure to toxic chemicals and particulate matter. Inhaled toxins impair ciliary function Dysregulation of immunity by cigarette smoking promotes inflammation and cancer: A review ScienceDirect Cigarette smoke triggers increased ACE 2 expression in the lung Immunopaedia What are the effects of smoking on lungs?

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