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[170] Filming began in March 1969, but six weeks into production, Mankiewicz slipped a disk at his home and directed the rest of the film from a wheelchair

The accuracy of the studies themselves, being cross-sectional, do not allow for causal inference and can sometimes overestimate relative risks given

Etiology Mechanical trauma (e.g., fingernail, paper edge, tree branch) Chemical injuries, medicamentosa keratitis Foreign body Contact lens Misdirected eyelashes Neurotrophic or exposure keratopathy Iatrogenic (e.g., after removal of corneal sutures, epithelial debridement) Symptoms Pain, especially upon blinking

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