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Key figures include: Tobacco smoking is responsible for around 8 million deaths annually worldwide (including about 1.3 million related to passive smoking) The risk of death for a smoker is about three times higher than for a non-smoker Tobacco smoking accounts for about 30% of all cancers and 90% of lung cancer cases Tobacco smoking is the cause of 25% of deaths from heart disease Tobacco smoking contributes to 10% of deaths from stroke Practical tips Choose a specific day within the next 12 weeks and treat it as a milestone moment

The level of mitofusin 2 (Mfn 2), a protein involved in mitochondrial dynamics responsible for mitochondrial fusion and tethering of mitochondria to ER, was also not significantly changed following nicotine treatment (Godoy et al