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[64] They were also designed to be equally addictive, as manufacturers did not want to lose customers

The Vapor Technology Association has advocated for raising the age to 21 for all tobacco products, including e-cigarettes, and believes, along with the public health groups, that this is the most significant step that can be taken to reduce youth access and use," Tony Abboud, executive director of the Vapor Technology Association, said in an emailed statement on Friday

Studies have also shown increase in M1/M2 macrophages and mast cells in people who smoke and patients with COPD [44,45,46]