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These rules reflect broader packaging requirements and aim to improve product safety and awareness of health risks associated with vaping

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A large body of evidence showed that direct skin exposure to cigarette smoke containing a large number of oxidants and radical species 40 leads to lipid peroxidation 41 associated with the skin barrier impairment demonstrated by the increased TEWL in various experimental models 5, 6 as well as in the cheek of smokers 4