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Premium artisanal blends rarely come in 5lb bags, so bulk options skew toward value pricing, but that reflects market positioning rather than quality degradation from bulk packaging itself

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Researchers found some evidence that non-serious adverse effects were more common in people receiving nicotine e-cigarettes compared to behavioral support only or no support, and a low number of unwanted effects, including serious effects, were found in studies comparing nicotine e-cigarettes to nicotine replacement therapy