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15 The 2018 National Academies of Sciences, Engineering, and Medicine report on the public health consequences of e-cigarettes concluded that there is limited evidence to demonstrate ENDS effectiveness when used in conjunction with tobacco cessation efforts, citing study limitations based on evidence drawn exclusively from laboratory testing of ENDS ingredients

By the 1980s and 1990s, studies began to show that second-hand smoke exposure also increased cancer risk, leading to widespread public smoking bans in workplaces, restaurants, and, eventually, film sets and studios