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Lastly, nicotine also has peripheral vasoconstrictive or bronchoconstrictive effects ( Finally, the Amazonian epistemic concepts that play a role in tobacco-based treatments as per our informant are consistent with traditional Amazonian conceptions of healing and sickness in general (e.g., concept of plants with agency, concept of spiritual/energetic factors in pathogenesis and treatment

Surgeon General's Warning: Smoking by Pregnant Women May Result in Fetal Injury, Premature Birth and Low Birth Weight

Grant's tobacco - General Ulysses Simpson Grant, during the Civil War, standing in front of his tent, holding cigar