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In a 1982 memo, the then-editor of JAMA cautioned the journals editorial staff to exercise appropriate caution in our JAMA publications on tobacco and control of tobacco use, nuclear war, and abortion. In providing this preventive advice, he noted that sensitivities are particularly high prior to the meetings of the Board of Trustees and the Annual and Interim Meetings of the House of Delegates. But what about other major health professional organizations and medical specialty associations

Therefore, nicotine increases the production of IL12 in DCs and stimulates the activation of T cells, which is followed by augmented IL2 production and increased CD40L expression