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LITERATURE REVIEW 1) Cigarette smoking effects on the respiratory epithelium The epithelium coating the upper respiratory tract acts as a first line of defense against invasive agents (pollutants, allergens, microorganisms), and it can cause upper airway symptoms and diseases when in contact with these agents.5 Inhaled cigarette smoke, both passively as well as actively, has been associated with chronic irritation and discomfort on the eyes, nose and oropharynx.6 Since 1964, when a report was published about smoking by the U.S

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Lung Cancer 90:121127 Balkwill FR, Mantovani A (2001) Inflammation and cancer: back to Virchow

OConnor and her team received bags full of death threats