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A human crossover study in 18 healthy adults found that a CBD-dominant brownie containing 640 mg of CBD increased exposure to a CYP3A probe drug by 56%, while a THC-dominant brownie produced no significant effect on the same enzyme

Spice was found to cause anxiety, hallucinations, psychosis, and paranoia in some users

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The labelling requirement for duty-paid cigarettes will help buyers and enforcement officers to differentiate duty-paid cigarettes from illicit cigarettes, including the so-called cheap whites. Authorities said there was no legal definition of cheap whites, but the term is generally used for less-well-known cigarette brands