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One study found that out of 50 strains of Gardnerella vaginalis, the majority were resistant to both metronidazole and clindamycin ( in vivo data, they indicate there is increasingly convincing evidence of antimicrobial resistance in BV and a need to address this in clinical management ( Failure of antimicrobial Lactobacillus to recolonize the vagina following antibiotic therapy may be another reason for high BV recurrence