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While nicotine is still partly used in third countries (as a pesticide or as a tobacco preparation), it is no longer authorized as a pesticide active substance in plant protection products in the EU since 2010, due to its high toxicity [1]

Increased carbon dioxide levels: Smoking affects the gas exchange process in your lungs, resulting in higher levels of carbon dioxide in your bloodstream

This accounts for more than half of all smoking- related deaths

Inter-individual variability in microbiome composition, transient colonization following microbial supplementation, and the lack of standardized endpoints to evaluate therapeutic efficacy collectively impede progress