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If our hypothesis pans out, then dopamine movies may help explain why nicotine-replacement therapies, such as nicotine patches, appear to be more effective for male smokers than for women. The study was supported by the National Institute on Drug Abuse and the National Institutes of Health Office of Research on Womens Health, through the Yale Translational Center to Develop Gender-Sensitive Treatment for Tobacco Dependence

Also, their nutrient requirements are different from many other plants, so adding a bit of gravel or special fertilizer designed for tobacco is a good idea