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Practical nicotine considerations for choosing between formats: Regular cigarettes deliver more total nicotine per cigarette Slim cigarettes contain less tobacco but similar nicotine concentration Actual nicotine intake depends more on smoking behavior than cigarette size Switching from regular to slim doesn't automatically reduce nicotine exposure 3

50year trends in smokingrelated mortality in the United States

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All scans were performed under local institution-approved guidelines for fMRI scans on healthy subjects to ensure adherence to ICH-GCP standards