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The Academies report also states there is moderate evidence that youth who use e-cigarettes are at increased risk for cough and wheezing and an increase in asthma exacerbations. E-cigarettes both contain and emit a number of potentially toxic substances. Health risks of e-cigarettes: A study from the University of North Carolina found that the two primary ingredients found in e-cigarettespropylene glycol and vegetable glycerinare toxic to cells and that the more ingredients in an e-liquid, the greater the toxicity

tobacco cigarettes and waterpipes increased the risk of lung cancer by 1210% (strong) and 122% (strong) respectively, while the level of evidence for e-cigarettes was not sufficient to draw reliable conclusions