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Effects of cigarette nicotine content and smoking pace on subsequent craving and smoking

Some of the signs of depression are: feeling sad or empty feeling discouraged or hopeless losing interest in things you usually enjoy having difficulty concentrating or making decisions feeling restless or irritable losing your appetite or eating too much feeling tired or without energy having difficulty sleeping or, for some people, sleeping too much

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[50] Increasing evidence indicates that the genetic variant CHRNA5 predicts the response to smoking cessation medicine