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Once we had estimated the age attenuation factors, we carried out the last step, which consisted of adjusting the risk curve for the reference age group from step 1 using equation (1) to produce the age group-specific risk curves for each CVD outcome: We implemented the age adjustment at the draw level so that the uncertainty of the age attenuation factors could be naturally incorporated into the final adjusted age-specific RR curves

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In Sweden, the share of men who smoked daily was 0.9 percentage points (pp) less than the share of daily female smokers, while in Denmark the proportion of male smokers who smoked daily was 0.1 pp less than the share of daily female smokers

Even gentle inhalation can generate enough negative pressure to dislodge a forming clot, particularly during the first 24-72 hours when the clot remains most vulnerable