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The image cancerous lesion on lip has the potential to positively impact youth behavior in addition to adult and young adult behavior. The FDA disagreed with comments that the image was too gross to be effective and that oral cancer was an odd choice of cancers to depict in the graphic warning, noting that the research literature indicates that images that evoke strong emotional reactions can promote greater awareness and better recollection of the health risks of smoking and can increase the likelihood smokers will reduce their smoking, make an attempt to quit, or quit altogether

Later, in 2019, Massachusetts became the first state to ban the sale of all flavored e-cigarette liquids and tobacco products [52], with New Jersey [53], as well as New York, and Rhode Island banning all flavors outside of tobacco or menthol the following year [54]