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Long term consequences of prenatal exposure to gutkha were demonstrated in mice, where the adult male offspring exposed to a high fat diet developed histological evidence of non-alcoholic fatty liver disease in addition to significant alterations in hepatic fibrosis-related cytokines (interleukin (IL)-1b and IL-6) and in hepatic collagen mRNA expression levels compared to control (non-exposed) group (Doherty Lyons et al., 2020)

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The mayor made it clear that the same policy would be followed for all similar applications

Amon men and women younger than 55 years, more than half of asymptomatic individuals had no detectable CAC