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The study showed that short-term exposure to mainstream tobacco smoke or sidestream tobacco smoke (STS), the main component of second-hand smoke, induces mutations at an expanded simple tandem repeat locus ( Ms6-hm ) in mouse sperm

Unlike cigarettes, they do not burn tobacco but rather contain a heating element that aerosolizes a nicotine-containing solution into a vapor, which users then inhale

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Tobacco smoke condensate induced antimicrobial peptide production in the Paneth cells and decreased bactericidal activity, making mice more susceptible to bacterial infection and leading to inflammation in the ileum (35)