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What is nicotine and other facts PMI Philip Morris International Health Problems Caused by Secondhand Smoke Smoking and Tobacco Use CDC Cigarettes contain numerous harmful chemicals that damage nearly every organ in the body. Nicotine, one of the most well known substances, increases heart rate and blood pressure, contributing to cardiovascular issues. But nicotine What Happens to Your Body, When You Take a Puff of a Cigarette? Keck Medicine of USC
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