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Mechanisms of cannabinoid activity The physiological effects of cannabis are primarily mediated through the ECS, a complex network comprising cannabinoid receptors (CB1 and CB 2 ), endogenous cannabinoids (anandamide and 2-arachidonoylglycerol) and associated enzymes (39)

China has not adjusted tobacco taxes in recent years, while household incomes have continued to rise, making cigarettes more affordable

Vaping is 95% less harmful than smoking, according to Public Health England (6), but a survey from Action on Smoking and Health found that 40% of UK smokers wrongly believe vaping is as harmful or even worse than smoking