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"So it seemed like a natural hypothesis to say, 'If we engage the GLP-1 system, we can reduce drug taking and seeking behaviors as well.'" The drug may also help prevent weight gain when smokers quit GLP-1 receptor agonists could be an especially "natural fit" for smokers who want to quit, Schmidt said, since they buffer against one thing that can keep people puffing: Fear of weight gain

This meant that they were regulated by the General Product Safety Regulations 2005 (GPSR)

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Nicotine creates a temporary boost in energy and mood by increasing dopamine levels in the brain