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Transporter-mediated approach for brain delivery of drugs Great efforts have been taken to deliver drugs into the brain, which resulted in the development of several drug delivery strategies (67,68,69,70)

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The source of the ROS might differ in the early, intermediate and late stages of obesity, switching from NOX4-dependence in the early phases to NOX2-dependence, in the intermediate phase, and transiting to mitochondria-dependence later in the time course of obesity

Xue, X.-C., Wu, Y.-J., Gao, M.-T., Li, W.-G., Zhao, N., Wang, Z.-L., Bao, C.-J., Yan, Z., & Zhang, Y.-Q